A direct-sequence spread-spectrum communication system for integrated sensor microsystems

Some of the most important challenges in health-care technologies have been identified to be development of noninvasive systems and miniaturization. In developing the core technologies, progress is required in pushing the limits of miniaturization, minimizing the costs and power consumption of microsystems components, developing mobile/wireless communication infrastructures and computing technologies that are reliable. The implementation of such miniaturized systems has become feasible by the advent of system-on-chip technology, which enables us to integrate most of the components of a system on to a single chip. One of the most important tasks in such a system is to convey information reliably on a multiple-access-based environment. When considering the design of telecommunication system for such a network, the receiver is the key performance critical block. The paper describes the application environment, the choice of the communication protocol, the implementation of the transmitter and receiver circuitry, and research work carried out on studying the impact of input data characteristics and internal data path complexity on area and power performance of the receiver. We provide results using a test data recorded from a pH sensor. The results demonstrate satisfying functionality, area, and power constraints even when a degree of programmability is incorporated in the system

Design of a single-chip pH sensor using a conventional 0.6-μm CMOS process

A pH sensor fabricated on a single chip by an unmodified, commercial 0.6-/spl μm CMOS process is presented. The sensor comprises a circuit for making differential measurements between an ion-sensitive field-effect transistor (ISFET) and a reference FET (REFET). The ISFET has a floating-gate structure and uses the silicon nitride passivation layer as a pH-sensitive insulator. As fabricated, it has a large threshold voltage that is postulated to be caused by a trapped charge on the floating gate. Ultraviolet radiation and bulk-substrate biasing is used to permanently modify the threshold voltage so that the ISFET can be used in a battery-operated circuit. A novel post-processing method using a single layer of photoresist is used to define the sensing areas and to provide robust encapsulation for the chip. The complete circuit, operating from a single 3-V supply, provides an output voltage proportional to pH and can be powered down when not required

Tunable photonic crystal filter for terahertz frequency applications

In this Paper we investigate a tunable metallic photonic crystal filter with a novel mechanical tuning method, suitable for use in terahertz frequency applications. Tuning has been demonstrated in a micrometer-driven prototype at 70 - 110 GHz in accordance with rigorous full-vector electromagnetic simulations (finite-difference time-domain). The measured pass band has a Q of 11 and can be tuned over a 3.5 GHz range. The insertion loss is only 1.1 to 1.7 dB, while the stop band attenuation is >10 dB. The filter has the advantages of inexpensive, robust and compact construction and tunable operation that readily scales to any desired terahertz frequency

A system-on-chip digital pH meter for use in a wireless diagnostic capsule

This paper describes the design and implementation of a system-on-chip digital pH meter, for use in a wireless capsule application. The system is organized around an 8-bit microcontroller, designed to be functionally identical to the Motorola 6805. The analog subsystem contains a floating-electrode ISFET, which is fully compatible with a commercial CMOS process. On-chip programmable voltage references and multiplexors permit flexibility with the minimum of external connections. The chip is designed in a modular fashion to facilitate verification and component re-use. The single-chip pH meter can be directly connected to a personal computer, and gives a response of 37 bits/pH, within an operating range of 7 pH units

In situ characterization of two wireless transmission schemes for ingestible capsules

We report the experimental in situ characterization of 30-40 MHz and 868 MHz wireless transmission schemes for ingestible capsules, in porcine carcasses. This includes a detailed study of the performance of a magnetically coupled near-field very high-frequency (VHF) transmission scheme that requires only one eighth of the volume and one quarter of the power consumption of existing 868-MHz solutions. Our in situ measurements tested the performance of four different capsules specially constructed for this study (two variants of each transmission scheme), in two scenarios. One mimicked the performance of a body-worn receiving coil, while the other allowed the characterization of the direction-dependent signal attenuation due to losses in the surrounding tissue. We found that the magnetically coupled near-field VHF telemetry scheme presents an attractive option for future, miniturized ingestible capsules for medical applications

Calculated and measured transmittance of a tunable metallic photonic crystal filter for terahertz frequencies

A tunable metallic photonic crystal filter with a mechanical tuning mechanism is demonstrated. The performance is predicted with rigorous full-vector electromagnetic simulations (finite-difference time domain). A prototype has been built and characterized in the W band (70–110 GHz) using a vector network analyzer configured for free-space measurement of S parameters. The measured filter's passband has a quality factor of 11, a tuning range of 3.5 GHz, and insertion loss of only 1.1–1.7 dB. Device fabrication is straightforward, yielding an inexpensive, robust and compact tunable filter

Radiation from ingested wireless devices in bio-medical telemetry bands

The performance of wireless devices, using electrically small antennae, in the human intestine is investigated using the finite difference time domain method in recommended biomedical device telemetry bands. The radiation field intensity was found to depend on position but more strongly on frequency, with a transmission peak at 650 MHz

Electromagnetic radiation from ingested sources in the human intestine between 150 MHz and 1.2 GHz

The conventional method of diagnosing disorders of the human gastro-intestinal (GI) tract is by sensors embedded in cannulae that are inserted through the anus, mouth, or nose. However, these cannulae cause significant patient discomfort and cannot be used in the small intestine. As a result, there is considerable ongoing work in developing wireless sensors that can be used in the small intestine. The radiation characteristics of sources in the GI tract cannot be readily calculated due to the complexity of the human body and its composite tissues, each with different electrical characteristics. In addition, the compact antennas used are electrically small, making them inefficient radiators. This paper presents radiation characteristics for sources in the GI tract that should allow for the optimum design of more efficient telemetry systems. The characteristics are determined using the finite-difference time-domain method with a realistic antenna model on an established fully segmented human body model. Radiation intensity outside the body was found to have a Gaussian-form relationship with frequency. Maximum radiation occurs between 450 and 900 MHz. The gut region was found generally to inhibit vertically polarized electric fields more than horizontally polarized fields

Variable-rate data sampling for low-power microsystems using modified Adams methods

A method for variable-rate data sampling is proposed for the purpose of low-power data acquisition in a small footprint microsystem. The procedure enables energy saving by utilizing dynamic power management techniques and is based on the Adams-Bashforth and Adams-Moulton multistep predictor-corrector methods for ordinary differential equations. Newton-Gregory backward difference interpolation formulae and past value substitution are used to facilitate sample rate changes. It is necessary to store only 2m+1 equispaced past values of t and the corresponding values of y, where y=g(t), and m is the number of steps in the Adams methods. For the purposes of demonstrating the technique, fourth-order methods are used, but it is possible to use higher orders to improve accuracy if required

Hybridization of optical plasmonics with terahertz metamaterials to create multi-spectral filters

Multi-spectral imaging systems typically require the cumbersome integration of disparate filtering materials in order to work simultaneously in multiple spectral regions. We show for the first time how a single nano-patterned metal film can be used to filter multi-spectral content from the visible, near infrared and terahertz bands by hybridizing plasmonics and metamaterials. Plasmonic structures are well-suited to the visible band owing to the resonant dielectric properties of metals, whereas metamaterials are preferable at terahertz frequencies where metal conductivity is high. We present the simulated and experimental characteristics of our new hybrid synthetic multi-spectral material filters and demonstrate the independence of the metamaterial and plasmonic responses with respect to each other